NEUROENDOVASCULAR COILING OF BERRY ANEURYSMS IN A PATIENT WITH AUTOSOMAL-DOMINANT POLYCYSTIC KIDNEY DISEASE: WHEN TO SOUND THE ALARM
DOI:
https://doi.org/10.32896/cvns.v7n4.1-8Keywords:
surveillance, therapeutic embolization, anterior cerebral artery, Aneurysm, Autosomal Dominant Polycystic KidneyAbstract
Background: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most prevalent inherited cause of end-stage renal disease. A critical extra-renal manifestation is the development of saccular intracranial aneurysms or berry aneurysms, which significantly increase morbidity and mortality in these patients.
Case Report: A 50-year-old female with a known right middle cerebral artery (MCA) aneurysm presented with persistent headache. Follow-up imaging five years later revealed the interval development of a new aneurysm in the right anterior cerebral artery (ACA) and an increase in the size of the original right MCA lesion. Successful endovascular coil embolization was performed, resulting in complete lesion obliteration and symptom resolution.
Conclusion: Intracranial aneurysms represent a serious threat in patients with ADPKD. Prompt intervention is indicated, particularly for high-risk individuals demonstrating signs of aneurysm growth, which suggests impending rupture. Endovascular coil embolization offers a safe and minimally-invasive management approach. For optimal screening efficiency, baseline Magnetic Resonance Angiography (MRA) screening is recommended starting at 30 years of age for high-risk patients.
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