PRIMARY CENTRAL NERVOUS SYSTEM T- CELL LYMPHOMA OF THE BRAIN IN AN IMMUNOCOMPETENT PATIENT
DOI:
https://doi.org/10.32896/cvns.v5n2.9-18Keywords:
Immunocompetent, Immunocompromised, primary central nervous system lymphoma, T-cell lymphoma, B-cell lymphoma, Magnetic Resonance Imaging (MRI)Abstract
PRIMARY CENTRAL NERVOUS SYSTEM T- CELL LYMPHOMA OF THE BRAIN IN AN IMMUNOCOMPETENT PATIENT
Primary central nervous system (PCNS) T-cell lymphoma is a rare disease and rarer if it is seen in immunocompetent patients. The PCNS lymphoma makes up 1-7% of primary brain tumors. PCNS T-cell lymphoma accounts for about 2% of all PCNS lymphoma and almost 99% are seen in immunocompromised patients (Latta et al 2010, Batchelor et al 2003). Here, we report a case of PCNS T-cell lymphoma in an elderly patient who is immunocompetent. The radiological findings, histopathological studies, and reviews of the current literature of this rare condition are discussed.
References
Batchelor, T., Carson, K., Niel, A. O., Grossman, SA., Alavi, J., New, P., Hochberg, F. and Priet, R.. Treatment of Primary CNS Lymphoma with Methotrexate and Deferred Radiotherapy: a report of NABTT 96-07, Journal of Clinical Oncology, vol. 21, no. 6, March, 2003 pp. 1044-1049.
Behbahani, M. and Lyons, M. K. Primary Central Nervous System T-cell Lymphoma of the Brain, The Open Neurosurg Journal, vol. 4, no. 1, 2011 pp. 62-65.
Bhagavathi, S. and Wilson, J. D. Primary Central Nervous System Lymphoma, Archives of Pathology & Laboratory Medicine, vol. 132, no. 11, 2008 pp. 1830-1834.
Giannini,C. Dogan, A., Salomão, R. CNS Lymphoma: A Practical Diagnostic Approach, Journal of Neuropathology & Experimental Neurology, Volume 73, Issue 6, June 2014, Pages 478–494
Da Silva, A. N., Lopes, M. B. and Schiff, D. Rare Pathological Variants and Presentations of Primary Central Nervous System Lymphomas, Neurosurgical focus, vol. 21, no. 5, 2006 pp. 1-6.
Erdag, N., Bhorade, R. M., Alberico, R. A., Yousuf, N. and Patel M. R. Primary lymphoma of the central nervous system: typical and atypical CT and MR imaging appearances, American Journal of Roentgenology, vol. 176, no. 5, 2001 pp. 1319-1326.
Ferreri, A. J. M., Blay, J. Y., Reni, M., Pasini, F., Spina, M., Ambrosetti, A., Calderoni, A., Rossi, A., Vavassori, V., Conconi, A., Devizzi, L., Berger, F., Ponzoni, M., Borisch, B., Tinguely, M., Cerati, M., Milani, M. Orvieto, E., Sanchez, J., Chevreau, C., Dell’Oro, S, Zucca, E. and Cavalli, F. Prognostic scoring system for primary CNS lymphomas: the International Extranodal Lymphoma Study Group experience, Journal of Clinical Oncology, vol. 21, no. 2, 2003 pp. 266-272.
Guan, H., Wen, W., Xu, M., Zan, Q. and Zhang, Z. Primary Central Nervous System Extranodal NK/T-Cell Lymphoma, Nasal Type: Case Report and Review of the Literature, Journal of Neuro-Oncology, vol. 103, no. 2, 2011 pp. 387-391.
Han, C.H. and Batchelor, T.T. (2017), Diagnosis and management of primary central nervous system lymphoma. Cancer, 123: 4314-4324.
Kim, M. K., Cho, C. H., Sung, W. J, Ryoo, H. M, Lee, H. J., Youn, S. W. and Park, K. K. Primary anaplastic large cell lymphoma in the dura of the brain: case report and prediction of a favorable prognosis, International Journal of Clinical Experimental Pathology, vol. 6, no. 8, 2013 pp. 1643-1651.
Latta, S., Myint, Z. W., Jallad, B., Hamdi, T., Alhosaini, M. N., Kumar, D. V. and Kheir, F. Primary central nervous system T-cell lymphoma in AIDS patients: case report and literature review, Current Oncology, vol. 17, no. 5, 2010 pp. 63-66.
Levin, N., Soffer, D., Grissaru, S., Aizikovich, N., Gomori, J. M. and Siegal, T. Primary T-cell CNS lymphoma presenting with leptomeningeal spread and neurolymphomatosis, Journal of Neuro-Oncology, vol. 90, no. 1, 2008 pp. 77-83.
Osborn A. G., Salzman, K. L., Jhaveri, M. D. and Barkovich, A. J. Diagnostic Imaging: Brain, Philadelphia: Elsevier Health Sciences, 2015.
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
